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E-085 The scepter mini catheter allows for improved penetration of fine vascular networks and facilitates curative embolization in vein of galen malformations
  1. A Devarajan,
  2. A Schupper,
  3. C Rossitto,
  4. J Bonet,
  5. M Sorscher,
  6. P Morgenstern,
  7. S Ghatan,
  8. T Shigematsu,
  9. A Berenstein,
  10. J Fifi
  1. Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA


Introduction Patients with Vein of Galen malformations (VOGM) can develop significant angiogenesis leading to hemodynamic and structural remodeling. This results in an extensive fine angiogenic network with fistulous connections to the vein of Galen. In patients with angiogenic networks, transarterial embolization (TAE) with liquid embolic agents (LEA) is challenging due to poor penetration and access, while transvenous approaches carry a risk of hemorrhage from pathologic vasculature. Dual-lumen balloon microcatheters such as the Scepter Mini (Microvention, Aliso Viejo, CA) improve navigability and distal pedicle access in small vessels. Here, we report on the novel use of the Scepter Mini for TAE of angiogenic VOGM.

Methods A single-institution retrospective chart review identified all patients with VOGM treated with Scepter Mini balloon microcatheters. Clinical data, angioarchitecture pre-embolization and post-embolization, and technical parameters including complications and embolization success were reviewed.

Results 17 Scepter Mini catheters were used in 12 embolizations of seven patients with VOGM. The median patient age at embolization was 2.10 years old. Patients presented with hydrocephalus (n=7, 100%) and gross motor and speech delays (n=4, 57.14%). Anatomically, fine vascular networks developed extra-axially into the subependymal zone from the posterior choroidal, posterior cerebral, and thalamoperforator arteries. Distal access to the network and VOGM was most commonly achieved within posterior choroidal branches (n=5/17, 29.41%). Successful embolization with Onyx-18 was achieved in 17/17 (100%) uses with all patients angiographically demonstrating significant network penetration. Near tip entrapment of the Scepter Mini with concurrent significant LEA cast displacement on removal occurred in 1/17 uses. One patient experienced postprocedural intraventricular hemorrhage requiring third ventriculostomy without permanent neurologic deficit.

Conclusions The Scepter Mini provided excellent distal access with penetration to the fistula and subsequent extra-axial network reduction with few complications. The Scepter Mini provides a means for successful treatment of angiogenic VOGM who present early and symptomatically, facilitating curative embolization.

Disclosures A. Devarajan: None. A. Schupper: None. C. Rossitto: None. J. Bonet: None. M. Sorscher: None. P. Morgenstern: None. S. Ghatan: None. T. Shigematsu: None. A. Berenstein: 2; C; Microvention. J. Fifi: 2; C; Microvention.

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