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E-164 Symptomatic developmental venous anomaly thrombosis associated with covid-19 infection
  1. B Eby,
  2. M Khasawneh
  1. Neurology, Washington University in STL, Saint Louis, MO, USA

Abstract

Developmental venous anomalies (DVA) are the most common type of cerebral vascular malformations with a prevalence of 3% of the general population. Despite their high prevalence, DVAs are rarely symptomatic. Only two occurrences of DVA thrombosis in the setting of COVID-19 infection have been recorded in medical literature. In both instances, venous infarction was associated with hemorrhagic transformation requiring decompressive craniectomy. We describe a milder case of DVA thrombosis in the setting of COVID-19 infection presenting with unilateral hemiparesis requiring medical management alone. A 41-year-old female with hypertension who presented with left hemiparesis. Non-contrast computed tomography (CT) of head revealed linear calcifications in the right centrum semiovale consistent with DVA. Magnetic resonance imaging (MRI) revealed an acute ischemic stroke in the right corona radiata adjacent to the vascular abnormality. Extensive workup for other causes of ischemic stroke was unrevealing. Cerebral angiography ruled out arteriovenous shunting and did not demonstrate DVA, consistent with DVA thrombosis. This case highlights a milder presentation of symptomatic DVA thrombosis associated with COVID-19 infection compared to the described literature.

Disclosures B. Eby: None. M. Khasawneh: None.

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