Article Text

Download PDFPDF

P005/44  Using the pEGASUS-stent with antithrombogenic properties and single antiplatelet therapy in a case of thrombectomy
  1. Nadja Krug,
  2. Victor Schulze-Zachau,
  3. Nikolaos Ntoulias,
  4. Marios Psychogios
  1. University Hospital Basel, Department of Diagnostic & Interventional Neuroradiology, Radiology & Nuclear Medicine Clinic, Basel, Switzerland
  2. *Live Presentation


Introduction Rescue stenting is used more and more in stroke cases with large-vessel-occlusion or medium-vessel-occlusion refractory to mechanical thrombectomy. The pEGASUS-stent(Phenox) represents a device which is equipped with a hydrophilic polymer coating(HPC) with antithrombogenic properties. The coating allows for implantation under single antiplatelet therapy, thus possibly reducing the risk of bleeding in acute stroke cases.

Case History A 79-year-old woman was rushed to emergency room due to left-sided hemiparesis and National-Institutes-of-Health-Stroke-Scale(NIHSS) of 14. Computed-tomography-image showed an occlusion of right posterior communicating artery(PCOM). Intravenous thrombolysis was initiated. Due to relevant clinical deficits an additional mechanical thrombectomy-maneuver was decided (figure 1A+B).

There was a persisting stenosis following the first (figure 1C) and re-occlusion following the second thrombectomy-maneuver (figure 1D). After exclusion of intracranial hemorrhage with a flat-detector-CT, an interdisciplinary decision was made in favor of rescue-stenting of re-occluded PCOM. Considering the fact that the patient was already under medication with Edoxaban (transient ischemic attacks in the past) the pEGASUS-HPC-stent (3.5x15 mm) was chosen. Prior to stenting 300mg of Aspirin were injected intravenously. After angioplasty with NeuroSpeed-balloon-catheter 2x8 mm (Acandis) the stent could be successfully deployed (figure 1E) and complete reperfusion was achieved (figure 1F). Monotherapy with Aspirin 100mg/d was started and during 17 days of hospital stay no new neurological deficits or ischemic events occurred. After follow-up-MRI and CT-Angiography at day 3 showed no extensive infarction and confirmed patency of the stent, dual antiplatelet therapy with Aspirin(100mg/d) and Clopidogrel(75mg/d) was started. The patient was discharged from hospital with an NIHSS of 2.

Disclosure of Interest Nothing to disclose

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.