Introduction Epidural blood patch (EBP) involves injecting autologous blood into the epidural space, with the aim of sealing off the site of cerebrospinal fluid (CSF) leak secondary to dura tear, as well as increase the intracranial pressure by mass effect causing CSF from the spinal compartment to enter the intracranial compartment. Current evidence demonstrates efficacy of EBP in managing low CSF pressure syndrome, which could be secondary to various etiology including post dura puncture, as well as spontaneous intracranial hypotension (SIH).

Aim of Study We aim to report our local pathway and outcomes in performing EBP in a tertiary centre.

Methods Retrospective data analysis performed to identify all patients treated with EBP our center. Total of 110 procedures were identified over the past 5 years. Outcomes are categorized as complete, partial (more than 3 months), inadequate (0–3 months), or no relief. Patients should at least return to their daily activities to be considered as a relief to symptoms. Other data collection includes basic demographics and indication for referrals.

Results Patients recorded were predominantly female (74 vs 36). Median age is 44 years old. Most common indication for referral includes SIH, post dura puncture headache (PDPH) or low pressure headaches. 29 cases had complete response, 28 had partial response, 26 had inadequate response and 27 had no response.

Conclusion Our experience demonstrates the role of EBP in managing patients with low CSF pressure symptoms in our center, with approximately 50% of cases reporting at least more than 3 months symptom relief.

Disclosure of Interest Nothing to disclose for all authors.