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P039/328  Endovascular treatment in cerebral venous thrombosis: safety and efficacy in an international two-center registry
  1. João Sousa1,
  2. Maider Iza Achutegui2,
  3. Jesús Juega3,
  4. Manuel Requena3;4,
  5. Carolina Chaves5,
  6. Marta Olivé3,
  7. Federica Rizzo3,
  8. Marián Muchada3,
  9. Jorge Pagola3,
  10. David Rodriguez-Luna3,
  11. Marta Rubiera3,
  12. Ana Inês Martins1,
  13. Fernando Silva1,
  14. Ricardo Veiga5,
  15. Cesar Nunes5,
  16. Egídio Machado5,
  17. David Hernández4,
  18. Marta de Dios Lascuevas4,
  19. Marc Ribo3,
  20. Alejandro Tomasello4,
  21. João Sargento Freitas1,
  22. Carlos A Molina3
  1. 1Centro Hospitalar e Universitário de Coimbra, Serviço de Neurologia, Coimbra, Portugal, Coimbra, Portugal
  2. 2Hospital Universitario Vall d’Hebron, Servicio de Neurología, Barcelona, Spain
  3. 3Hospital Universitario Vall d´Hebron, Unidad de Ictus, Servicio de Neurología, Barcelona, Spain
  4. 4Hospital Universitario Vall d´Hebron, Unidad de Neurorradiología Intervencionista, Barcelona, Spain
  5. 5Centro Hospitalar e Universitário de Coimbra, Departamento de Neurorradiologia, Coimbra, Portugal


Introduction The standard acute treatment of Cerebral Venous Thrombosis (CVT) is anticoagulation. After several uncontrolled studies and one randomized clinical trial, there is still uncertainty regarding the role of endovascular treatment (EVT) in this scenario.

Aim of Study To evaluate safety and efficacy of EVT in CVT combined with best medical care.

Methods We performed a retrospective analysis of an international two-center registry.

Results EVT was performed in 20% (12/58) of CVT patients with a median time from diagnosis to treatment of 4.5h (1.25–28.5). Compared to medical therapy alone, EVT patients had higher baseline NIHSS [median 5.5 (2–17) vs 0 (0–3) p=0.004] and basal CT showed higher rates of intracerebral hemorrhage (41.7% vs 6.4%, p=0.006). EVT was performed using transjugular access in half of the patients and transfemoral access in the other half. Aspiration with large bore catheters was performed in every case with angioplasty in 7 out of 12 patients and stenting in 3 out of 12 patients. Recanalization was achieved in 75% of the patients with a median time from puncture to recanalization of 90 (74.3–157.5) minutes. No postprocedural complications were observed. We found a significant improvement from baseline to discharge median NIHSS in patients submitted to EVT [5.5 (2–17) vs 1(0–3.75) p<0.001].

Conclusion In our series, endovascular treatments in CVT combined with anticoagulation was safe and efficacious as evidenced by angiographic findings and clinical improvement.

Disclosure of Interest Nothing to disclose

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