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P052/6  Long-term follow-up after aneurysm treatment with the flow redirection endoluminal device (FRED) flow diverter
  1. Sophia Hohenstatt1,
  2. Christian Ulfert1,
  3. Christian Herweh1,
  4. Tim Hilgenfeld1,
  5. Niclas Schmitt1,
  6. Silvia Schönenberger2,
  7. Min Chen2,
  8. Martin Bendszus1,
  9. Markus Möhlenbruch1,
  10. Dominik Vollherbst1
  1. 1University Hospital Heidelberg, Neuroradiology, Heidelberg, Germany
  2. 2University Hospital Heidelberg, Neurology, Heidelberg, Germany
  3. *Live Presentation


Introduction The Flow Re-Direction Endoluminal Device (FRED; MicroVention) and its version dedicated for smaller vasculature FRED Jr. (MicroVention) belong to the worldwide most frequently used FD. Several studies showed a good efficacy of the FRED and FRED Jr. with a good safety profile in the short and mid-term. However, to date there are no targeted long term-follow-up data covering more than five years for these devices.

Aim of Study This study focuses on long-term outcomes after aneurysm treatment with either the FRED or the FRED Jr. to investigate the durability of treatment effect and long-term complications.

Methods Patients treated with either FRED or FRED Jr. between 2013 and 2017 at our institution, and thus a possibility for ≥5 years of follow-up, were retrospectively analysed. Aneurysm occlusion rates, recurrence rates, modified Rankin Scale score shifts to baseline, and delayed complications were assessed.

Results 68 patients with 84 aneurysms had long-term follow-up with a mean duration of 57.3 months. 44 patients harbouring 52 aneurysms had a follow-up ≥5 years with a mean follow-up period of 69.2 months. Complete occlusion was reached in 77.4% at two years and increased to 84.9% when the latest available imaging result was considered. After the two-years threshold, there were three reported symptomatic non-serious adverse events.

Conclusion This long-term follow-up study demonstrates that the FRED and FRED Jr. are safe and effective for the treatment of cerebral aneurysms in the long-term, with high rates of complete occlusion and low rates of delayed adverse events.

Disclosure of Interest Nothing to disclose.

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