Introduction Few studies have compared the Pipeline Shield stents with previous generations of flow-diverting stents (FDs) for treating unruptured intracranial aneurysms (IA).

Aim of Study This study aimed to evaluate the efficacy and safety of Pipeline Shield stents and FDs without modified surfaces.

Methods The present evaluation is a retrospective cohort study of patients endovascularly treated for unruptured IA. The data analyzed was obtained from the anonymized database of the institution’s Interventional Radiology service.

Results The aneurysms treated with Pipeline Shield stents had higher six-month (OKM D; 87.5% vs. 71.4%, p-value: 0.025) and one-year (OKM D; 82.5% vs. 63.0%, p-value: 0.047) occlusion rates than aneurysms treated using FDs without modified surfaces. No differences between the devices were found at the one-year follow-up in ischemic stroke (p-value: 0.939) and hemorrhagic complications (p-value: 0.559).

Conclusion The treatment with Pipeline Shield stent was as safe as with FD stent without modified surfaces. However, they showed a greater occlusion efficacy during one-year evaluation period.

Disclosure of Interest othing to disclose