Introduction Several studies have been conducted on sarcopenia occurring during the stroke recovery process; however, few studies have observed the functional prognosis of patients with sarcopenia following stroke.

Aim of Study In this study, sarcopenia was investigated by measuring early skeletal muscle mass in patients with ischemic stroke, and the functional outcome of patients with ischemic stroke with sarcopenia was analyzed.

Methods Patients diagnosed with ischemic stroke within 7 days of symptom onset who underwent dual-energy X-ray absorptiometry were enrolled. Sarcopenia was diagnosed based on Asian Working Group for Sarcopenia (AWGS) and European Working Group on Sarcopenia in Older People (EWGS). The outcome was functional status, measured as mRS score at discharge and at 3 months. Outcomes were grouped into dichotomous categorical variables (mRS: 0–3 vs. 4–6) and poor functional outcome (mRS of 4–6).

Results An mRS score of 4–6 was assigned to 89 patients and an mRS score of 0–3 was assigned to 564 patients. The group diagnosed with sarcopenia at stroke onset had a significantly higher proportion of poor functional scores. Multivariable logistic regression analysis, with functional outcome as a response variable, revealed that height-adjusted appendicular skeletal muscle mass (ASM) and EWGS for sarcopenia were independently associated.

Conclusion Ischemic stroke patients with an early diagnosis of sarcopenia (according to EWGS and AWGS) had a significantly higher risk of poor functional outcome. Height-adjusted ASMs may play an important role in predicting poor functional outcomes

Disclosure of Interest none