Introduction Stroke is a leading cause of mortality and morbidity worldwide. Intracranial atherosclerotic disease (ICAD) accounts for nearly 50% of ischemic strokes caused by large artery atherosclerosis.

Aim of Study To demonstrate effectiveness of intracranial stenting with angioplasty as method to decrease recurrent stroke and increase cerebral blood flow in symptomatic ICAD

Methods Patients referred to Hospital San Carlos Borromeo from 2021 with acute cerebral ischemia or history of transient cerebral ischemia with ICAD documented in angiography that underwent intracranial balloon assisted angioplasty and stent placement.

6 and 12 months follow-up with AngioCT or DSA to ensure patency of stented vessel, neurological examination and chart review to assess effectiveness of procedure preventing future stroke events.

Results Total patients treated with angioplasty and intracranial stenting were 19(n). Median age was 63,4 (48 – 82). 11 patients were treated acutely (57,9%), 8 elective patients (42,1%). 10 patients were placed on antiplatelet and antiaggregant therapy (52,7%), 2 on antiplatelet (10,5%), 7 on antiaggregant (36,8%). Cardiac stent was placed In 4 patients (21,1%), 15 intracranial stents (78,9%). There were 9 anterior circulation stenosis (47,3%), 10 posterior circulation stenosis (52,7%). 2 patients died from unrelated causes and were excluded in final analysis.

Follow-up images showed patency of stented vessels with flow augmentation compared to inicial DSA (17, 100%), No new cases of acute stroke, TCI nor neurological deficits were documented.

Conclusion Intracranial Stenting with balloon assisted angioplasty is a safe and effective procedure to reduce recurrent stroke events and to restablish cerebral blood flow.

Disclosure of Interest Nothing to disclose