Introduction Cerebral vasospasm (CV) after aneurysmal subarachnoid hemorrhage (aSAH) worsen the neurological prognosis. The Neurospeed is a novel cerebral non compliant balloon device.

Aim of Study We report our first cases of intracranial angioplasty in CV with Neurospeed.

Methods This is part of the SAVEBRAINPWI prospective single-center observational study (ClinicalTrials.gov: NCT05276934) to assess CV management. Patients were treated as per our local protocol if they had CV>50% compared to the baseline imaging, and clinical symptoms. The vessel diameters were measured before and after angioplasty. The primary endpoint was the percentage of improvement in vessel diameter immediately after treatment with the Neurospeed compared with the baseline.

Results Four patients with a mean age of 58 years and mean mFisher of 3 were treated.

A total of 14 vessels were treated.

The mean pre-treatment stenosis of the vessel was 68% with reduction of the narrowing to 19% after treatment. No immediate complication occurred.

Conclusion The Neurospeed balloon device appears safe and effective to regain vessel diameter in intracranial vasospasm after aSAH. This balloon offers a new precise tool allowing for controlled vessel expansion in intracranial vasospasm.

Disclosure of Interest Consultancy for Rapid Medical and Phenox