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Does signal without noise and noise without signal exist?
  1. Matthias Gawlitza,
  2. Karl-Titus Hoffmann,
  3. Cindy Richter
  1. Department of Neuroradiology, Leipzig University Hospital, Leipzig, Germany
  1. Correspondence to Dr Cindy Richter; cindy.richter{at}medizin.uni-leipzig.de

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We thank Saad and Booth for their interest in our study1 and for their comments.2 We are aware that with our study, just as they state, the precise reason for non-ischemic cerebral enhancing (NICE) lesions associated with flow diverters (FD) cannot be accurately established. The careful reader will recognize that we too were surprised by the results, and that we did not claim to be sure how they could be explained. Still, can we consider these numbers to be only noise without signal?

The difference in the incidence of cases with NICE lesions was large – 0% vs 3.7% and 3.3% when comparing the device family associated with fewer NICE cases (let us call it product A to avoid any company names) with the two device …

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Footnotes

  • Contributors All authors contributed equally.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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