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SNIS 21st annual meeting electronic poster abstracts
E-040 In-stent stenosis in the pipeline embolization device: a systematic review and meta-analysis
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  1. S Patel1,
  2. J Lee2,
  3. S Palepu2,
  4. G Sioutas2,
  5. J Burkhardt2,
  6. V Srinivasan2
  1. 1Thomas Jefferson University, Philadelphia, PA
  2. 2Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA

Abstract

Introduction In-stent stenosis (ISS) is a poorly understood complication of treatment with the Pipeline Embolization Device (PED). The inconsistency in defining ISS across studies further complicates efforts to understand its predictors and risk factors.

Methods A systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews (PRISMA-ScR) guidelines was conducted using PubMed, Scopus, EMBASE, and Web of Science

Results We identified a total of 51 relevant studies. 12 studies reported as 0% rate of ISS. The total number of patients was 4082, with 424 documented cases of ISS. The mean rate of ISS was 10.3%. For each study, we report the degree of stenosis that the authors used as the threshold for ISS.

Conclusions To our knowledge, we compile the largest review of PED cases with data from over 4000 patients. We report a general incidence of ISS with the PED and note that ISS is a relatively rare complication of treatment with the PED. Our descriptive analysis underscores the considerable variability in ISS definitions employed across studies, highlighting the need for standardized criteria to facilitate more robust comparisons and analyses in future research endeavors.

Abstract E-040 Figure 1
Abstract E-040 Figure 1

Disclosures S. Patel: None. J. Lee: None. S. Palepu: None. G. Sioutas: None. J. Burkhardt: None. V. Srinivasan: None.

https://doi.org/10.1136/jnis-2024-SNIS.145

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