Article Text

Download PDFPDF

E-118 A single-center study of the RED 72 reperfusion catheter with SENDit technology in proximal large vessel occlusions
Free
  1. V Dhar1,
  2. P Barrera1,
  3. S Akkipeddi1,
  4. A Gunturi1,
  5. M Cotroneo1,
  6. C Houk1,
  7. L Thompson1,
  8. D Schartz2,
  9. N Ellens1,
  10. T Mattingly1,
  11. T Bhalla1,
  12. M Bender1
  1. 1Neurosurgery, University of Rochester Medical Center, Rochester, NY
  2. 2Imaging Sciences, University of Rochester Medical Center, Rochester, NY

Abstract

Introduction/Purpose SENDit technology (Penumbra Inc, Alameda CA) is a novel supple, tapered obturator used instead of a microcatheter to bring up the RED72 aspiration catheter during endovascular thrombectomy (EVT). It was designed to speed materials setup and overcome the ‘ledge’ effect.

Materials and Methods This was a single-institution observational study of EVT for anterior circulation large vessel occlusion affecting the ICA, M1, or M2. Cases were collected from January 2022 to March 2024; SENDit was introduced in August 2023 at our institution. Statistical tests used were difference in proportions, two-sample t-test, and chi-square test of independence.

Results There were no significant differences between the SENDit (n=33) and comparison groups (n=198) in age, gender, presenting NIHSS, laterality, or time since last known well. 50.0% of occlusions in the SENDit group and 64.6% of occlusions in the comparison group were in the M1 branch (p=0.084, z=-1.750). The proportion of M2 occlusions was 7.5% in the SENDit group and 1.9% in the comparison group (p=0.048, z=1.981). ICA occlusions comprised 42.5% of the SENDit cases and 33.5% of comparison cases (p=0.273, z=1.096). The rate of tandem occlusions in the SENDit group was 21.2% and 7.6% in the comparison group (p=0.013, z=2.471).

First pass rate (TICI ≧ 2b-3) was 42.4% in SENDit cases and 31.8% in comparison cases (p=0.231, z=1.197). Final recanalization ≥TICI2b was 90.9% in the SENDit group and 95.0% in the comparison group (p= 0.351, z=-0.932).There was no association between SENDit usage and rates of hemorrhagic infarction (ECASS HI-1 or HI-2 grade) and parenchymal hematoma (ECASS PH-1 or PH-2 grade) (χ² =2.255, p=0.324). HI and PH collectively were observed in 33.3% of SENDit cases and 43.4% of cases in the comparison group (p=0.276, z=-1.088).For patients with available follow-up, the rate of functional independence (mRS 0–2) at discharge was 21.2% for SENDit cases and 11.1% for the comparison group (p=0.105, z=1.621).Stentrievers were used in 18.2% of SENDit cases as compared to 56.1% of cases in the comparison group (p<0.001, z=-4.029). The average materials cost in SENDit cases was $8,105.73 ± $3329.96 versus $10,029.65 ± $5,062.88 in the comparison group (p=0.036, t=2.106).

Conclusion In this observational series of anterior circulation proximal LVO, use of SENDit technology was associated with lower rates of stentriever use and decreased procedure cost. There was no difference in complications, reperfusion rates, or clinical outcomes.

Disclosures V. Dhar: None. P. Barrera: None. S. Akkipeddi: None. A. Gunturi: None. M. Cotroneo: None. C. Houk: None. L. Thompson: None. D. Schartz: None. N. Ellens: None. T. Mattingly: None. T. Bhalla: None. M. Bender: None.

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.