Introduction The direct aspiration first pass technique (ADAPT) is an effective and safe endovascular treatment for M2 occlusions in acute ischemic stroke patients. Appropriate aspiration catheters are crucial for a successful ADAPT maneuver.

Aim of Study To report technical features and initial results of a novel reperfusion catheter (RED 62) used for frontline ADAPT of acute M2 occlusions.

Methods All patients treated with ADAPT using RED 62 as frontline treatment approach for acute M2 occlusions in two tertiary stroke centers (12/2022 - 02/2024) were retrospectively enrolled. Demographic data, procedural timings and safety, recanalization rates and outcome data were recorded.

Results 20 patients with a median admission NIHSS score of 8 (IQR 9) were identified. Successful revascularization (DMVO-TICI ≥2b) with ADAPT was obtained in 65% (13/20). The first pass effect was 45% (9/20). In two cases, the RED 62 did not reach the clot due to marked distal vessel tortuosity. Stent retrievers were additionally used in 9 cases and led to an overall DMVO-TICI 2c/3 of 90% (18/20). Mean procedural time was 48 minutes. No complications directly related to ADAPT occurred. In-hospital mortality rate was 20% (4/20). At discharge, median NIHSS score was 2.5 (IQR 6), and 55% (11/20) had a mRS 0-2.

Conclusion Our initial experience with the novel RED 62 reperfusion catheter for treatment of M2 occlusions is in line with published data. ADAPT using this catheter may be considered as a safe and effective first-line treatment option. Further studies are warranted to validate the initial results.

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Abstract P144 Figure 1

Disclosure of Interest no.