Introduction eCLIPs combines both coil retention and flow diversion by bridging the neck of WNBA. We describe eCLIPs implant experience to date using 2 delivery systems: i) via hypotube with requisite .034’ microcatheter, eBRS, and ii) via guidewire, compatible with smaller microcatheters, eB.

Aim of Study We report the entire eCLIPs experience for safety and efficacy: 280 patients, 101 eBRS and 179 eB.

Methods Procedural data were collected prospectively and follow up data were collected according to usual clinical practices.

Results Implant procedural success rate was 88%, 82% for eBRS, 92% for eB. 35% of cases were recurrences, 20% prior rupture. Anatomy: 89% cases were basilar tip and carotid terminus locations. Mean followup 38 mo: Safety: Procedural neurologic death: 3% eBRS, 0% eB (overall 1.1%), CVA 3% eBRS, 1.1% eB (overall 1.8%), repeat procedure (all with inadequate neck-bridging) 2.5%. No patient had post-procedural thrombo-embolic or other neurologic safety events. Efficacy: Of 82 patients with eBRS implants, 61 meet eligibility criteria for a WEB-IT-patterned trial; all available 57 patients of this cohort had follow-up imaging, many with multiple imaging timepoints. Forty patients with eB implants have had follow-up > 6 months. Modified Raymond Roy Occlusion Classification (for all patients) 1 = 80%, 2 = 16%. No patient had regression of mRROC score on serial follow-up imaging.

Conclusion eCLIPs has a satisfactory safety profile; introduction of lower-profile eCLIPs delivery system, eliminating large microcatheters and complex sidebranch access, resulted in lower procedural complications and improved procedural success. Durable adequate occlusion is 96%.

Disclosure of Interest yes Co-founder Evasc Neurovascular.