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  • P013 Woven EndoBridge device or stent assisted coiling for treatment of the intracranial bifurcation aneurysms: a systematic review and meta-analysis

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Abstracts
Haemorrhagic
1.1. Aneurysms
P013 Woven EndoBridge device or stent assisted coiling for treatment of the intracranial bifurcation aneurysms: a systematic review and meta-analysis
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  1. Mohammad Amin Dabbagh Ohadi1,2,
  2. Amir Asef2,
  3. Mohammad Dashtkoohi2,
  4. Raha Zamani2,
  5. Basel Musmar3,
  6. Ali Zomorodi3,
  7. David Hasan3
  1. 1Department of Pediatric Neurological Surgery, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2Tehran University of Medical Sciences, Tehran, Iran
  3. 3Department of Neurosurgery, Duke University Hospital, Durham, NC, USA

Abstract

Introduction The Woven EndoBridge (WEB), an intrasaccular disruption device, offers a novel option for complex aneurysms, particularly bifurcation aneurysms.

Aim of Study In this systematic review and meta-analysis, we aim to compare the safety and efficacy of WEB devices with stent-assisted coiling (SAC) for intracranial bifurcation aneurysms.

Methods We systematically searched PubMed, Scopus, and Embase databases in October 2023 following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We aimed to compare aneurysmal occlusion, procedural time, retreatment, and complication rates as secondary objectives. The comparison between the two techniques was performed using a weighted random-effects model, and the quality of the studies was assessed using the Newcastle-Ottawa Scale (NOS) for cohort studies.

Results The authors analyzed five studies encompassing 298 and 203 patients in SAC and WEB groups, respectively. Complete (53.8%, OR, 0.97; 95%CI: 0.63-1.49, I2= 0%) and adequate (77.8%, OR: 0.88; 95%CI: 0.51-1.5, I2= 0%) occlusion didn’t differ between two groups. The overall procedural time mean difference was 38.2 minutes, significantly higher in the SAC group (95%CI, 26.9-49.6, I2=53.4%). Retreatment rates did not significantly differ between the two groups (OR: 1.34; 95%CI: 0.37-4.85, I2=61.7%). The SAC group experienced more complications during and after the operation (OR, 2.82; 95%CI: 1.07-7.44, I2=0%). The pooled follow-up duration was 22.1 and 13.5 months for the SAC and WEB groups respectively.

Conclusion The WEB demonstrates comparable efficacy in occluding bifurcation aneurysms compared to SAC, with the added benefits of reduced procedural time and lower complication rates.

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Disclosure of Interest no.

https://doi.org/10.1136/jnis-2024-ESMINT.50

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