Article Text
Abstract
Introduction Up to 30% intracranial Mechanical Thrombectomies (MT) may not result in recanalization due to an underlying stenosis, dissection or tough clot. Bail-out stenting has been reported to be a treatment option to achieve recanalization and good clinical outcome.
Aim of Study In the Rescue Stenting with CREDO® Heal for Recanalisation after Unsuccessful Thrombectomy (RECHRUT) study the efficacy and safety of the coated CREDO® heal for Bail-out stenting is evaluated.
Methods RECHURT is a prospective, single-arm, multicentre, open-label international PMCF study. Patients treated with CREDO® heal due to acute ischemic stroke and large vessel occlusion after unsuccessful MT and suspected underlying stenosis are included. Technical success is defined as mTICI 2b-3 recanalization and good clinical outcome at 90 (±20) days as mRS 0-2.
Results Starting in March 2023, eighteen patients have been enrolled by 8 of 17 participating European sites. Mean age was 71 years and mean mRS at admission was 3.2. Treatment was successful in all cases achieving mTICI 2b-3 recanalization in 100%. Mean mRS at discharge was 2.2; mRS at 90d was available in 9 patients with 0-2 in 78%. Mean stenosis grade was 82% before and 28% after PTA and stenting. Periprocedural severe adverse events occurred in 33%. No recurrent occlusions occurred. GP IIb/IIIa antagonists were administered periprocedurally and switched two dual antiplated therapy during the hospital stay.
Conclusion The RECHRUT study is including patients and the early interim analysis shows technical and clinical success in line with the literature of rescue stenting.
Disclosure of Interest yes Speaker Honoraria by Acandis.