Purpose To evaluate the clinical results of the endovascular treatment of ruptured intracranial aneurysms using GDC and matrix coils.

Materials and methods A prospective, multicenter registry was conducted in France from October 2006 to June 2007 in 19 neurointerventional centers to compare the endovascular treatment of ruptured aneurysms with GDC and matrix coils. 405 patients were treated with GDC coils and 377 with matrix coils.

Results Endovascular treatment failed in 3/405 cases (0.7%) in the GDC group and in 2/377 cases (0.5%) in the matrix group. Adverse events related to the treatment were encountered in 71/405 patients (17.5%) in the GDC group and in 68/377 patients (18.0%) in the matrix group. Thromboembolic events were encountered in 54/405 patients (13.3%) in the GDC group and in 45/377 patients (11.9%) in the matrix group, intraoperative rupture in 15/405 patients (3.7%) in the GDC group and in 19/377 patients (5.0%) in the matrix group and early rebleeding in 2/405 patients (0.5%) in the GDC group and in 4/377 (1.1%) in the matrix group. Finally, morbidity and mortality to the treatment were, respectively, 4.0% (16/405) and 1.5% (6/405) in the GDC group and 4.0% (15/377) and 1.3% (5/377) in the matrix group.

Conclusion The CLARITY study demonstrates that the immediate safety of the endovascular treatment of ruptured intracranial aneurysms using GDC and Matrix coils is similar with low morbidity and mortality with both types of coils.