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Effects of a music intervention on patients undergoing cerebral angiography: a pilot study
  1. Teresa L Vanderboom1,
  2. Patricia M Arcari2,
  3. Mary E Duffy3,
  4. B Somarouthu4,
  5. James D Rabinov1,
  6. Albert J Yoo1,
  7. Joshua A Hirsch1
  1. 1Interventional Neuroradiology, Massachusetts General Hospital, Boston, Massachusetts, USA
  2. 2Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
  3. 3Yvonne L Munn Center for Nursing Research, Massachusetts General Hospital, Boston, Massachusetts, USA
  4. 4Interventional Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA
  1. Correspondence to T L Vanderboom MSN, RN, ANP-BC, Interventional Neuroradiology, Massachusetts General Hospital, 55 Fruit Street, Gray 241, Boston, MA 02114, USA; tvanderboom{at}


Purpose To test the effect of a music intervention on procedural anxiety, stress response and medication requirements in participants with a cerebral aneurysm or arteriovenous malformation (AVM) undergoing cerebral angiography.

Method and materials A prospective pilot study was conducted using an experimental two group pre-test, post-test design. 48 participants were randomly assigned to a control group (standard care) or experimental group (standard care plus self-selected music via overhead stereo system). The stress response was measured by heart rate (HR) and systolic blood pressure (SBP) at baseline, and during and following the procedure. Anxiety was measured by the State Trait Anxiety Inventory for Adults (STAI) before and after the procedure, and total medications administered periprocedurally were recorded.

Results 24 participants in each group were enrolled. R-ANCOVA revealed non-significant findings for HR (F=1.4; p=0.27; power=0.38) and SBP (F=2.1; p=0.10; power=0.57). The ANCOVA for anxiety revealed significantly lower STAI scores in the control group (F=3.8; p=0.003) compared with the experimental group. Independent t test analysis for the total doses of fentanyl and midazolam were found to be F=0.08, p=0.78 and F=0.38, p=0.54, respectively.

Conclusion A music intervention on participants with a brain aneurysm or AVM undergoing cerebral angiography did not have a statistically significant impact on reducing the stress response, anxiety or medication requirements. Interestingly, participants in the control group had significantly less anxiety after their angiogram than did participants in the experimental group. This pilot study sets the stage for future research to further examine these findings.

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  • Funding Yvonne L Munn Center for Nursing Research at Massachusetts General Hospital: Nursing Research Award $1500.00. Theta Alpha Chapter of the Sigma Theta Tau International Honor Society of Nursing: Anne K Kibrick Research Award $750.00.

  • Competing interests None.

  • Ethics approval This study was conducted with the approval of the Partners Human Research Committee.

  • Provenance and peer review Not commissioned; internally peer reviewed.