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Case report
Pathologic validation of clot length determined using thin section non-contrast CT
  1. Albert J Yoo1,2,
  2. Thabele M Leslie-Mazwi1,
  3. Christian H Riedel3,
  4. Ronil V Chandra1
  1. 1Department of Radiology, Division of Interventional Neuroradiology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA
  2. 2Department of Radiology, Division of Diagnostic Neuroradiology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA
  3. 3Department of Neuroradiology, University of Kiel, Kiel, Germany
  1. Correspondence to Dr A J Yoo, 55 Fruit Street, Gray 241, Boston, MA 02114, USA; ajyoo{at}


Background and purpose Recent studies have demonstrated that in acute ischemic stroke patients, thin section non-contrast CT (NCCT) can be used to determine the length of the hyperdense intracranial thrombus, and that clot length using this approach predicts the likelihood of vessel recanalization after intravenous tissue plasminogen activator.

Summary of case An acute ischemic stroke patient presented with a left middle cerebral artery occlusion and underwent emergent catheter based therapy. Clot length was determined using pretreatment thin section NCCT and was independently confirmed by the pathologist after whole clot extraction.

Conclusions The concordance between the NCCT measured clot length and the pathological examination in this case provides additional support for the accuracy of using thin section NCCT data to determine clot length in all patients.

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  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval Ethics approval was provided by the Massachusetts General Hospital institutional review board.

  • Provenance and peer review Not commissioned; externally peer reviewed.