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E-040 Initial Multi-Centre Experience with the Penumbra PC 400 Detachable Coil
  1. A Patel1,
  2. H Moyle1,
  3. I Chaudry2,
  4. D Frei3,
  5. R Bellon3,
  6. D Huddle3,
  7. B Baxter4,
  8. S Quarfordt4,
  9. R Turner2,
  10. A Turk2
  1. 1Neurosurgery and Radiology, Mount Sinai School of Medicine, New York, NY
  2. 2Medical University of South Carolina, Charleston, SC
  3. 3Swedish Medical Center, Englewood, CO
  4. 4Erlanger Hospital System, Chattanooga, TN


Introduction/Purpose Aneurysm coil technology has changed considerably since the introduction of the GDC coil. We evaluated our initial clinical experience with a novel 0.020 Penumbra PC 400 coil to determine device safety and acute performance.

Materials and Methods Between 2/2011 and 9/2012, 133 aneurysms were coiled with Penumbra PC 400 coils; 84 elective and 49 ruptured, at four high volume centres.

Results Average aneurysm size was 8 mm with 28% PCOM, 43% other ICA locations, 21% ACOM and the remaining Basilar, MCA and Vertebral. 15% of the cases were treated with balloon assisted coiling, 18% were stent assisted coiling, and 4% utilised both balloons and stents. Packing density could be accurately calculated in 97 aneurysms. Average packing density was 38.7%. 32% of the cases achieved an initial Raymond Scale of 1, 24% achieved a Raymond scale of 2, and 43% were Raymond Scale of 3. Almost half (66) of the patients have angiographic follow up at the time of this abstract. Based on the same/better/worse scale, vast majority of aneurysms showed stable or improved angiographic outcomes at 6 months and one year. Thirty-six had improved, 24 remained unchanged and 6 worsened, 0 patients required re-treatment. We experienced a 5% rate of peri-procedural adverse events. 3 (2%) were thromboembolic, all 3 patients were SAH cases, of which 2 had no clinical sequelae. 4 (3%) were aneurysm perforations, 3 with no clinical sequelae, and one SAH H/H grade 4 patient died, resulting in an overall morbidity and mortality of 2 (1.5%). We continue to use the coils and accrue follow up and will update results at the time of the meeting.

Conclusion The new Penumbra PC 400 coils are unique 0.020 coils that show very high average packing density and long term occlusion rates with a safe profile.

Disclosures A. Patel: 3; C; Penumbra, Inc. H. Moyle: None. I. Chaudry: 3; C; Penumbra, Inc. D. Frei: 3; C; Penumbra, Inc. R. Bellon: None. D. Huddle: None. B. Baxter: 3; C; Penumbra, Inc. S. Quarfordt: None. R. Turner: None. A. Turk: 3; C; Penumbra, Inc.

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