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Original research
Ultrashort imaging to reperfusion time interval arrests core expansion in endovascular therapy for acute ischemic stroke
  1. Mohammed A Almekhlafi1,2,
  2. Muneer Eesa3,
  3. Bijoy K Menon1,
  4. Andrew M Demchuk3,4,
  5. Mayank Goyal3,4
  1. 1Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
  2. 2Department of Internal Medicine, King Abdulaziz University, Jeddah, Western, Saudi Arabia
  3. 3Department of Diagnostic Imaging, University of Calgary, Calgary, Alberta, Canada
  4. 4Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
  1. Correspondence to Dr Mayank Goyal, Department of Radiology, Hotchkiss Brain Institute, University of Calgary, Foothills Medical Center, 1403 29th St NW, Calgary, AB, Canada T2N 2T9; mgoyal{at}


Background and purpose The shorter the time interval between the estimation of the ischemic core by imaging and reperfusion, the more likely that core expansion is minimized. We aimed to assess the feasibility of achieving an ultrashort imaging to reperfusion time in routine clinical practice.

The study subjects were a prospective cohort of patients with acute ischemic stroke treated with endovascular therapy in a tertiary center in whom an imaging to reperfusion time of <60 min was achieved.

Results Imaging to reperfusion time of <60 min was accomplished in 11 patients. The median baseline National Institutes of Health Stroke Scale (NIHSS) score was 11 and the median baseline Alberta Stroke Program Early CT Score (ASPECTS) was 8. The median time interval from imaging to endovascular reperfusion was 47 min. The median ASPECTS score on the 24 h CT scan was also 8 and the median 24 h NIHSS score was 1. Upon discharge, 82% of patients achieved a modified Rankin scale score of ≤1.

Conclusions An imaging to endovascular reperfusion time of <60 min is feasible and resulted in minimal core expansion on follow-up imaging in patients with acute ischemic stroke.

  • Stroke
  • Thrombectomy
  • Brain
  • CT
  • Intervention

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