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Understanding IMS III: old data shed new light on a futile trial
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  • Published on: 13 April 2016
    Considerations of alteplase as an intra-arterial lytic agent

    J. J. (Buddy) Connors MD, Interventional Neuroradiology, Vanderbilt University Medical Center, Nashville, TN.

    Re: Understanding IMS III: old data shed new light on a futile trial

    I read this article with great interest. The issue of tPA and its risk/benefit ratio for intra-arterial treatment of acute ischemic stroke is essential to understanding the results of IMS III. While possible toxic effects of...

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    Conflict of Interest:
    None declared.