Article Text

Download PDFPDF
E-051 Classification of Cavernous Internal Carotid Artery Tortuosity: A Predictor of Procedural Complexity in Pipeline Embolization
  1. C Uwandu1,
  2. L Lin2,
  3. G Colby2,
  4. J Huang2,
  5. R Tamargo2,
  6. A Coon2
  1. 1School of Medicine, Johns Hopkins University, Baltimore, MD, USA
  2. 2Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA


Background Endoluminal reconstruction of a diseased parent artery with flow diverters is increasingly used for the treatment of intracranial aneurysms. The complexity of these procedures can be highly variable. Understanding the degree of tortuosity of the cavernous internal carotid artery (ICA) may help predict procedural complexities of deploying flow diverters such as the Pipeline embolization device (PED).

Methods We retrospectively reviewed a prospective, single-center aneurysm database to identify all patients with ICA aneurysms proximal to the posterior communicating artery who underwent endovascular treatment using the PED with the Navien distal intracranial guide catheter. Cavernous ICA (cICA) tortuosity was measured as a ratio between the height difference of the cICA anterior and posterior genus (D) to the sum of the angles of the anterior and posterior genus (AP). Identified patients were categorized into three groups based on cICA tortuosity. An analysis of variance regression was performed to detect differences among the three groups as they relate to procedural fluoroscopy time length, cICA tortuosity (D/AP), and aneurysm size.

Results Seventy-eight cICA were analyzed and the degree of tortuosity was categorized into minimal (group I, n = 26), moderate (group II, n = 28), and severe or “Simmons-type” (group III, n = 24). The three groups were comparable with relation to patient age (mean group I – 55.5, II – 55.0, III – 55.9) and aneurysm size (mean group I – 6.2 mm, II – 7.8 mm, III – 9.0 mm). Analysis of variance demonstrated significant differences in procedural fluoroscopy time (FT) and degree of cICA tortuosity (D/AP). Mean FT was greater in group III (50.3 + 13.5) compared to group II (42.3 + 33.3) and group I (30 + 8.4), p value <0.005. Similarly, mean D/AP was significantly higher in group III (0.49 + 0.38) compared to groups II (0.14 + 0.07) and I (0.008 + 0.0008), p value <0.005. In group I, PED deployment was successful in 100% of cases whereas groups II and III had 2 and 1 unsuccessful cases respectively.

Conclusion In this study, we propose a classification system for cICA tortuosity based on measurements of the anterior and posterior genu geometry. This classification correlates strongly with markers of PED procedural complexity and may be helpful in pre-procedure prognostication.

Disclosures C. Uwandu: None. L. Lin: None. G. Colby: None. J. Huang: None. R. Tamargo: None. A. Coon: 2; C; ALC is a proctor for the Pipeline Embolization Device (Covidien, Mansfield, Massachusetts, USA) and a consultant for Covidien.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.