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Original research
The safety and efficacy of low profile visualized intraluminal support (LVIS) stents in assisting coil embolization of intracranial saccular aneurysms: a single center experience
  1. Zhengzhe Feng,
  2. Yibin Fang,
  3. Yi Xu,
  4. Bo Hong,
  5. Wenyuan Zhao,
  6. Jianmin Liu,
  7. Qinghai Huang
  1. Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China
  1. Correspondence to Dr Q Huang, Department of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Shanghai 200433, China; shchfzz141012{at}


Background The low profile visualized intraluminal support (LVIS) device is a new generation of self-expanding braided stents recently introduced into China for stent assisted coiling of intracranial aneurysms. This study assessed the clinical safety and efficacy of the LVIS stent for embolization of intracranial saccular aneurysms.

Methods Patients with intracranial saccular aneurysms treated using the LVIS device in our center between April 2014 and December 2014 were reviewed. The primary outcomes were procedural safety, target aneurysm recurrence, and mid-term follow-up of clinical and angiographic outcomes.

Results 97 patients with intracranial saccular aneurysms were treated using the LVIS stent, with 100% technical success rate. No mortality was observed. One patient had transient deficit (1/97, 1.0%). Immediate angiographic outcome evaluation showed complete occlusion in 28 (28.8%) and neck remnant in 39 (40.2%) of the 97 patients, respectively. Of the 76 (78.35%) patients who underwent angiographic follow-up at a mean of 8.1 months, complete occlusion was achieved in 64 (84.2%) patients. In the remaining patients, neck remnant in nine (11.8%) and residual sac in three (4%) patients were observed. None of the patients had any target aneurysm recurrence, and the mortality rate was 0%.

Conclusions The LVIS stent is safe and effective in the treatment of intracranial saccular aneurysms.

  • Aneurysm
  • Angiography
  • Stent
  • Intervention

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  • Contributors ZF and QH contributed equally to the preparation of the manuscript. ZF, YF, and WZ contributed equally to data collection. YX and BH contributed equally to clinical follow-up. QH and JL contributed equally to the interventional procedures.

  • Funding This research was supported by the Major Project of Shanghai Committee of Science and Technology (grant No 13411950300). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Ethics approval The study was approved by the institutional review board of Changhai Hospital.

  • Provenance and peer review Not commissioned; externally peer reviewed.