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Original research
Endovascular stroke therapy with the Aperio thrombectomy device
  1. Kai Kallenberg1,
  2. Laszlo Solymosi2,
  3. Christian A Taschner3,
  4. Joachim Berkefeld4,
  5. Marc Schlamann5,
  6. Olav Jansen6,
  7. Sebastian Arnold7,
  8. Bernd Tomandl8,
  9. Michael Knauth1,
  10. Bernd Turowski9
  1. 1Institute for Diagnostic and Interventional Neuroradiology, University Medical Center Göttingen, Göttingen, Germany
  2. 2Department of Neuroradiology, University Würzburg, Würzburg, Germany
  3. 3Department of Neuroradiology, University Medical Center Freiburg, Freiburg, Germany
  4. 4Institute for Neuroradiology, University Medical Center Frankfurt, J W Goethe-University Frankfurt, Frankfurt, Germany
  5. 5Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany
  6. 6Department of Radiology and Neuroradiology, UKSH Campus Kiel, Kiel, Germany
  7. 7Institute for Diagnostic and Interventional Radiology, Städtisches Klinikum Karlsruhe gGmbH, Karlsruhe, Germany
  8. 8Clinic for Radiology and Neuroradiology, Klinikum Christophsbad, Göppingen, Germany
  9. 9Section of Neuroradiology, Institute for Diagnostic and Interventional Radiology, University Düsseldorf, Düsseldorf, Germany
  1. Correspondence to Dr Kai Kallenberg, Diagnostic and Interventional Neuroradiology, Universtitätsmedizin Göttingen, Robert-Koch-Str. 40, Göttingen 37099, Germany; kai.kallenberg{at}


Background The pharmaceutical therapy for acute ischemic stroke has shortcomings in reopening large vessels and dissolving long thrombi, and endovascular treatment has been found to provide added value. The Aperio thrombectomy device showed promising results in an experimental study. The purpose of this study was to evaluate the device clinically.

Methods 119 patients with acute stroke were treated in nine centers using the Aperio thrombectomy device. Target vessel, diameter, thrombus length, procedure time, recanalization, number of deployments, additional use of anticoagulants, complications, and the use of additional devices were assessed.

Results The median thrombus length was 15 mm (range 1.5–20 mm) and the average time from device insertion to recanalization was 30 min (range 5–120 min). Blood flow restoration (Thrombolysis In Cerebral Infarction (TICI) 2–3) was achieved in 85%. In the majority of cases complete clot removal was achieved (TICI 0, 12%; TICI 1, 2%; TICI 2a, 14%; TICI 2b, 18%; TICI 3, 53%). The median number of deployments was 2 (range 1–6). Twelve procedural complications (10%) occurred.

Conclusions The Aperio thrombectomy device seems to be an effective and adequately safe tool for reopening occluded cerebral arteries in the setting of acute stroke.

  • Stroke
  • Thrombectomy
  • Device
  • Brain

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