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Case series
Endovascular treatment of posterior inferior cerebellar artery aneurysms: a 7-year single-center experience
  1. Feng Xu1,
  2. Yong Hong2,
  3. Yongtao Zheng1,
  4. Qiang Xu2,
  5. Bing Leng1
  1. 1Department of Neurosurgery, Huashan Hospital, Shanghai Medical School, Fudan University, Shanghai, China
  2. 2Department of Radiology, Huashan Hospital, Shanghai Medical School, Fudan University, Shanghai, China
  1. Correspondence to Professor Bing Leng, Department of Neurosurgery, Huashan Hospital, Shanghai Medical School, Fudan University, Shanghai 200040, China; lengbing12345678{at}


Aim To report our experience with endovascular treatment of posterior inferior cerebellar artery (PICA) aneurysms.

Methods Between January 2007 and December 2014, 40 patients with 42 PICA aneurysms were treated with endovascular embolization at our institution. Twenty-eight patients had 29 saccular aneurysms and 12 patients had 13 fusiform/dissecting aneurysms. The endovascular modalities were: (1) selective occlusion of the aneurysm with or without stent assistance (n=19); (2) occlusion of the aneurysm and the parent artery (n=22); and (3) occlusion of the aneurysm including the vertebral artery and PICA origin (n=1). Specifically, selective embolization was performed in 93.3% of aneurysms (14/15) proximal to the telovelotonsillary segment.

Results Immediate angiographic results included 31 complete occlusions (74%), 3 nearly complete occlusions (7%), and 8 incomplete occlusions (19%). Mean follow-up of 20 months in 31 aneurysms showed 27 stable results, 3 further thromoboses, and 1 recurrence. Final results included 27 complete occlusions (87.1%) and 4 incomplete occlusions (12.9%). There were 5 overall procedural-related complications (12.5%), including 1 infarction (2.5%) and 4 intraprocedural ruptures (10.0%). Procedure-related morbidity and morbidity was 5.0% (2/40) and 2.5% (1/40), respectively. Clinical outcome was excellent (Glasgow Outcome Scale 5 in 31 of 33 patients at long-term follow-up).

Conclusions PICA aneurysms may be effectively treated by different endovascular approaches with favorable clinical and radiologic outcomes. Further studies are required to compare the safety and efficacy of endovascular treatment with open surgery.

  • Aneurysm

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  • FX and YH contributed equally to this work.

  • Contributors Conception and design: FX. Acquisition of data: FX, YH, QX, YZ. Drafting the article: FX. Critically revising the article: FX. Review of submitted version of manuscript on behalf of all authors: FX, LB. Statistical analysis: ZY. Administrative/technical/material support: YH.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Ethics approval This retrospective study was approved by the Institutional Review Board at Huashan Hospital Fudan Hospital and all patients signed general informed consent forms.

  • Provenance and peer review Not commissioned; externally peer reviewed.