Introduction/Purpose Effective suction to M2 and beyond during acute stroke thrombectomy is challenging to ensure and essential to the timely removal of thrombus. We report significant increases in aspiration catheter performance utilizing a new nozzle-tip device design.

Materials and Methods 10 commercially available aspiration catheters, between 3 and 6 Fr, were compared with 5 Fr and 6 Fr prototype devices for fluid flow rate and suction force. A constant vacuum was supplied by a portable aspiration pump common to the clinical environment.

Results The nozzle-tip prototype, the Mi-R⁴Q, outperformed all comparable commercially available catheters. The 5 Fr Mi-R⁴Q prototype sustained a flow rate 24.7% greater than the next best aspiration catheter within 0.10 mm of the same tip ID, and retained 15.7% more of the supplied vacuum. The 6 Fr Mi-R⁴Q prototype sustained a flow rate 21.9% greater than the next best aspiration catheter within 0.03 mm of the same tip ID, and retained 15.9% more of the supplied vacuum. An in-vitro simulated ADAPT procedure yielded promising subjective data on the ease of use and reduction in complexity attained with use of the Mi-R⁴Q.

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Abstract O-030 Figure 1

Conclusion The Mi-R⁴Q demonstrates a substantial increase in aspiration catheter capability by applying known relationships in Fluid Dynamics to more effectively convey vacuum and aspirate fluid than anything else currently on the market. Simulated use validates effectiveness of design and paves the way for in-vivo study.

Disclosures A. Halaszyn: 1; C; MIVI Neuroscience Inc. A. Berenstein: 6; C; MIVI Neuroscience Inc.. T. Shigematsu: None. P. Coletti: None.