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ELVO: an operational definition
  1. Thabele Leslie-Mazwi1,
  2. Ronil V Chandra2,
  3. Blaise W Baxter3,
  4. Adam S Arthur4,
  5. Muhammad S Hussain5,
  6. I Paul Singh6,
  7. Don F Frei7,
  8. Richard P Klucznik8,
  9. Felipe C Albuquerque9,
  10. Joshua A Hirsch10
  11. the Society of NeuroInterventional Surgery
  1. 1Departments of Neurosurgery and Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
  2. 2Interventional Neuroradiology, Monash University, Melbourne, Australia
  3. 3Interventional Neuroradiology, Erlanger Health System, Chattanooga, Tennessee, USA
  4. 4Department of Neurosurgery, Semmes Murphey Clinic and University of Tennessee Health Sciences Center, Memphis, Tennessee, USA
  5. 5Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA
  6. 6Department of Neurosurgery, Mount Sinai Cerebrovascular Center, New York, USA
  7. 7Interventional Neuroradiology, Swedish Medical Center, Denver, Colorado, USA
  8. 8Department of Radiology, Houston Methodist, Houston, Texas, USA
  9. 9Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA
  10. 10Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA
  1. Correspondence to Dr Thabele Leslie-Mazwi; tleslie-mazwi{at}

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Recent landmark randomized controlled trial data1–7 have initiated a global transformational change in acute stroke therapy for ischemic stroke patients with large vessel occlusion. With endovascular thrombectomy established as the new standard of care for patients with large vessel occlusions, increased attention has turned towards service delivery to as many eligible patients as possible. The SNIS, in concert with other regional, national and international societies, has focused on this agenda.8 9 As both the need for and availability of endovascular thrombectomy grows, the terminology describing eligible patients requires uniformity. An operational definition of the clinical scenario in which a stroke patient has an urgent need for endovascular thrombectomy becomes increasingly important.10 11 A standardized nomenclature that uses consistently defined terms will facilitate continuous quality improvement as the field grows and understanding is advanced.12

Endovascular thrombectomy is a therapy specifically directed towards proximal cerebral vascular occlusions. Earlier studies with equivocal results for the benefit of this therapy13–15 were noteworthy for the absence of confirmation of pre-procedure vascular status. Recent positive trials were characterized by the requirement that vascular occlusion be documented as a requisite for patient enrollment in the trials.1–7 However, across these recent landmark trials there was significant variability in the definition of large vessel …

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  • Contributors All authors contributed to drafting and review of manuscript.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.