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We read with great interest the article by Bandaru et al1 in a recent issue of the Journal of NeuroInterventional Surgery in which they have identified that leukoaraiosis (LA) severity on pre-mechanical thrombectomy (MT) no contrast computed tomography (NCCT) is associated with worse 90-day outcomes in patients with acute ischemic stroke (AIS) following endovascular recanalization, and is an independent risk factor for worse outcomes. Moreover, they proposed a modification to the ASPECT score, L-ASPECTS, which combines ischemia with white matter injury on the basis of the original ASPECTS.2
In the latest BEST trial study,3 Mistry et al found that patients with moderate-to-severe LA had …
All the authors contributed equally to this letter.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; internally peer reviewed.