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Report from the society of magnetic resonance angiography: clinical applications of 7T neurovascular MR in the assessment of intracranial vascular disease
  1. Binbin Sui1,
  2. Bhagya Sannananja2,
  3. Chengcheng Zhu3,
  4. Niranjan Balu3,4,
  5. Laura Eisenmenger5,
  6. Hediyeh Baradaran6,
  7. Myriam Edjlali7,
  8. Javier M Romero8,
  9. Prabakhar Shantha Rajiah9,
  10. Rui Li10,
  11. Mahmud Mossa-Basha3,4
  1. 1Tiantan Neuroimaging Center of Excellence, China National Clinical Research Center for Neurological Diseases, Beijing, China
  2. 2Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia, USA
  3. 3Department of Radiology, University of Washington, Seattle, Washington, USA
  4. 4Vascular Imaging Lab, University of Washington School of Medicine, Seattle, Washington, USA
  5. 5Radiology, University of Wisconsin-Madison, Madison, Wisconsin, USA
  6. 6Department of Radiology & Imaging Sciences, University of Utah, Salt Lake City, Utah, USA
  7. 7Neuroradiology, Hospital Saint Anne, Paris, France
  8. 8Department of Radiology, Division of Neuroradiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
  9. 9Radiology, Mayo Clinic Minnesota, Rochester, Minnesota, USA
  10. 10Center for Biomedical Imaging Research, Tsinghua University, Beijing, China
  1. Correspondence to Dr Mahmud Mossa-Basha, Radiology, University of Washington, Seattle, WA 98195, USA; mmossab{at}; Dr Binbin Sui; reneesui{at}


In recent years, ultra-high-field magnetic resonance imaging (MRI) applications have been rapidly increasing in both clinical research and practice. Indeed, 7-Tesla (7T) MRI allows improved depiction of smaller structures with high signal-to-noise ratio, and, therefore, may improve lesion visualization, diagnostic capabilities, and thus potentially affect treatment decision-making. Incremental evidence emerging from research over the past two decades has provided a promising prospect of 7T magnetic resonance angiography (MRA) in the evaluation of intracranial vasculature. The ultra-high resolution and excellent image quality of 7T MRA allow us to explore detailed morphological and hemodynamic information, detect subtle pathological changes in early stages, and provide new insights allowing for deeper understanding of pathological mechanisms of various cerebrovascular diseases. However, along with the benefits of ultra-high field strength, some challenges and concerns exist. Despite these, ongoing technical developments and clinical oriented research will facilitate the widespread clinical application of 7T MRA in the near future. In this review article, we summarize technical aspects, clinical applications, and recent advances of 7T MRA in the evaluation of intracranial vascular disease. The aim of this review is to provide a clinical perspective for the potential application of 7T MRA for the assessment of intracranial vascular disease, and to explore possible future research directions implementing this technique.

  • MRI
  • vessel wall
  • stroke
  • magnetic resonance angiography

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  • Contributors All authors contributed substantially to the conception and design of the work, drafting and critically revising of the manuscript, final approval of the manuscript, and agree to be accountable for all aspects of the work. BS and MM-B provided and edited the figures.

  • Funding The project was supported with funding from NIH R01NS125635.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.