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Correspondence on ‘Non-ischemic cerebral enhancing (NICE) lesions after flow diversion for intracranial aneurysms: a multicenter study’ by Richter et al
  1. Saad Moughal1,
  2. Thomas C Booth2,3
  1. 1Department of Radiology, Manchester Royal Infirmary, Manchester, UK
  2. 2Department of Neuroradiology, King's College Hospital NHS Foundation Trust, London, UK
  3. 3School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK
  1. Correspondence to Dr Thomas C Booth, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK; thomas.booth{at}kcl.ac.uk

https://doi.org/10.1136/jnis-2024-021548

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    We read with interest the recent article by Richter et al.1 Non-ischaemic cerebral enhancing (NICE) lesions are a documented phenomenon occurring following endovascular therapy. It is postulated that an underlying inflammatory reaction to hydrophilic polymer embolic material is implicated in the pathogenesis. Several compositions of hydrophilic polymer materials including polytetrafluoroethylene and polyacrylamide are ubiquitously used as hydrophilic surface coatings of several endovascular devices.2 The purpose is to reduce the risk of endothelial damage and to enhance maneuverability to aid navigation. Historically the incidence of …

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    Footnotes

    • Twitter @ThomasCBooth

    • Contributors SM drafted the letter. TB contributed to the response and approved the final version.

    • Funding TCB is supported by the Wellcome/EPSRC Centre for Medical Engineering (WT 203148/Z/16/Z).

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; internally peer reviewed.

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