RT Journal Article SR Electronic T1 DynaCT evaluation of in-stent restenosis following Wingspan stenting of intracranial stenosis JF Journal of NeuroInterventional Surgery JO J NeuroIntervent Surg FD BMJ Publishing Group Ltd. SP 2 OP 5 DO 10.1136/jnis.2009.000505 VO 2 IS 1 A1 Moskowitz, S I A1 Kelly, M E A1 Haynes, J A1 Fiorella, D YR 2010 UL http://jnis.bmj.com/content/2/1/2.abstract AB Objective and importance To describe the use of DynaCT angiographic imaging for the evaluation of Wingspan in-stent restenosis (ISR).Methods Two patients were treated with Wingspan stenting and percutaneous transluminal angioplasty (Patient 1 had treatment of a severe stenosis of the right middle cerebral artery and patient 2 had severe stenosis of the left intracranial internal carotid artery. Both patients developed ISR and were evaluated with high resolution DynaCT angiographic imaging.Results DynaCT demonstrated circumferential soft tissue density material distributed within the stent as the cause of the stenosis visualized with conventional angiography.Conclusions These findings support the hypothesis that ISR is caused by neointimal proliferation, rather than vascular re-coil with stent collapse.