RT Journal Article SR Electronic T1 Endovascular treatment of basilar artery occlusion by manual aspiration thrombectomy JF Journal of NeuroInterventional Surgery JO J NeuroIntervent Surg FD BMJ Publishing Group Ltd. SP 110 OP 114 DO 10.1136/jnis.2009.001420 VO 2 IS 2 A1 Brian T Jankowitz A1 Aitziber Aleu A1 Ridwan Lin A1 Mouhammad Jumaa A1 Hilal Kanaan A1 Dean Kostov A1 Maxim Hammer A1 Ken Uchino A1 Larry R Wechsler A1 Michael Horowitz A1 Tudor G Jovin YR 2010 UL http://jnis.bmj.com/content/2/2/110.abstract AB Background and purpose Basilar artery occlusion remains one of the most devastating subtypes of stroke. Intravenous and intra-arterial therapy have altered the natural history of this disease; however, clinical results remain poor. Therefore, exploring more aggressive and innovative management is warranted.Methods Six consecutive patients presenting with a basilar artery occlusion were treated with the same general algorithm of intra-arterial tissue plasminogen activator and mechanical thrombectomy with the Merci retrieval system. If complete recanalization was not achieved after two passes, manual syringe aspiration through a 4.3F catheter was employed.Results All interventions utilizing aspiration thrombectomy resulted in recanalization, with five out of six cases displaying TIMI3/TICI3 flow and one patient resulting in complete recanalization of the basilar artery with persistent thrombus in one P2 segment (TIMI2/TICI2B). All patients survived, with five out of six independent in activities of daily living at 3 months (mRS 0–2).Conclusions Our small case series indicates that aspiration thrombectomy performed manually through a 4.3F catheter can facilitate recanalization of basilar artery occlusion with acceptable clinical outcomes.