TY - JOUR T1 - The Penumbra Stroke System: a technical review JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 199 LP - 205 DO - 10.1136/neurintsurg-2011-010080 VL - 4 IS - 3 AU - Albert J Yoo AU - Don Frei AU - Satoshi Tateshima AU - Aquilla S Turk AU - Ferdinand K Hui AU - Allan L Brook AU - Don V Heck AU - Joshua A Hirsch Y1 - 2012/05/01 UR - http://jnis.bmj.com/content/4/3/199.abstract N2 - Major ischemic strokes secondary to proximal artery occlusions are responsible for significant morbidity and mortality. Owing to extensive clot burden, these strokes are poorly responsive to intravenous tissue plasminogen activator. The introduction of endovascular therapy, particularly mechanical devices, has resulted in markedly improved recanalization rates of large vessel occlusions. With increasing experience with the Penumbra Stroke System and the 054 reperfusion catheter, there has been further improvement in TIMI 2 and 3 revascularization rates with faster times to vessel opening. The aim of this technical review is to convey various tips and tricks learnt from this experience. ER -