TY - JOUR T1 - 030 Preliminary data for the dawn trial (DWI/PWI and CTP assessment in the triage of wake-up and late presenting strokes undergoing neurointervention): imaging based endovascular therapy for proximal anterior circulation occlusions beyond 8 h from last seen well in 193 stroke patients JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 85 LP - 85 DO - 10.1136/jnis.2009.001016d VL - 1 IS - 1 AU - R Nogueira AU - D Liebeskind AU - R Gupta AU - E Levy AU - A Rai AU - A Barreto AU - O Zaidat AU - N Janjua AU - A Abou-Chebl AU - D Yavagal AU - M Rymer AU - B Baxter AU - A Furlan AU - T Jovin Y1 - 2009/07/01 UR - http://jnis.bmj.com/content/1/1/85.1.abstract N2 - Background: A large proportion of patients suffering acute strokes due to a proximal arterial occlusion present beyond the typical 8 h therapeutic window for endovascular intervention and thus are not considered candidates for reperfusion therapies. However, MRI perfusion and positron emission tomography studies have shown that a significant fraction of these patients have evidence of persistent penumbral tissue, suggesting the therapeutic window may be protracted in selected cases. We therefore hypothesized that imaging based endovascular therapy in wake up and late presenting stroke patients (defined as last seen well >8 h) is safe and potentially … ER -