PT  - JOURNAL ARTICLE
AU  - Christopher L Cummings
AU  - Johanna Morton
AU  - Thinesh Sivapatham
AU  - Irene Katzan
AU  - Ken Uchino
AU  - Thomas Masaryk
AU  - Muhammad Shazam Hussain
TI  - Centenarian middle cerebral artery occlusion treated with intra-arterial mechanical embolectomy
AID  - 10.1136/neurintsurg-2011-010082
DP  - 2012 Sep 01
TA  - Journal of NeuroInterventional Surgery
PG  - e23--e23
VI  - 4
IP  - 5
4099  - http://jnis.bmj.com/content/4/5/e23.short
4100  - http://jnis.bmj.com/content/4/5/e23.full
SO  - J NeuroIntervent Surg2012 Sep 01; 4
AB  - Advanced age, arbitrarily defined as over 80 years, has been an exclusion criterion in many clinical trials for the treatment of acute ischemic stroke. The oldest person, to our knowledge, treated for acute ischemic stroke with intra-arterial therapy is presented and, importantly, this patient was excluded from intravenous tissue plasminogen activator due to an advanced age of 100 years and arrival in our emergency department within the 3–4.5 h time window. Utilizing an MRI based protocol to assess the risk–benefit ratio, treatment by intra-arterial mechanical embolectomy was commenced resulting in middle cerebral artery recanalization at 6 h 30 min. The patient improved, and ultimately returned to a baseline modified Rankin Scale score of 3. With careful selection, elderly patients may benefit from acute stroke therapies and may be considered on a case by case basis.