RT Journal Article SR Electronic T1 E-019 Preoperative cortical localization by magnetic source imaging for endovascular treatment of arterial venous malformations in eloquent brain tissue JF Journal of NeuroInterventional Surgery JO J NeuroIntervent Surg FD BMJ Publishing Group Ltd. SP A39 OP A39 DO 10.1136/neurintsurg-2011-010097.85 VO 3 IS Suppl 1 A1 A Cho A1 S Pakbaz A1 J Bykowski A1 D Green A1 R Lee YR 2011 UL http://jnis.bmj.com/content/3/Suppl_1/A39.1.abstract AB Introduction Preoperative localization of functionally eloquent brain tissue helps plan and tailor the extent of endovascular embolization and surgical resection of AVMs. Combined magnetoencephalography and MR data can be used to localize functional somatosensory, auditory, and motor cortical organization.Materials and Methods Retrospective review of all AVMs treated (both endovascular and surgical) at our institution over the past 2 years. We identified 4 cases of AVMs involving eloquent cortical brain tissue with associated magnetic source imaging for localization of cortical organization. Case records were reviewed for patient outcome and impact of cortical organization localization of treatment and management.Results Combined magnetoencephalography and MR data had a high degree of reliability in localizing motor cortex in areas adjacent to and incorporated by AVMs. Localization of motor cortex affected AVM treatment plans focusing on preservation of motor cortex function.Conclusion Functional mapping of the cortex is indispensable for optimal treatment of AVMs involving eloquent brain tissue. The cases outlined demonstrate the capability of preoperative spatiotemporal functional brain mapping using MEG.