PT - JOURNAL ARTICLE AU - Thabele M Leslie-Mazwi AU - Ronil V Chandra AU - Daniel C Oh AU - Raul G Nogueira TI - Novel use of prasugrel for intracranial stent thrombosis AID - 10.1136/jnis.2010.004382 DP - 2011 Dec 01 TA - Journal of NeuroInterventional Surgery PG - 358--360 VI - 3 IP - 4 4099 - http://jnis.bmj.com/content/3/4/358.short 4100 - http://jnis.bmj.com/content/3/4/358.full SO - J NeuroIntervent Surg2011 Dec 01; 3 AB - Dual antiplatelet therapy is established for prevention of stent thrombosis in cardiac patients, and widely utilized in neurointerventional stent cases. Aspirin and clopidogrel are typically synergistic. We present a case of clopidogrel resistance due to genetic polymorphism resulting in acute stent thrombosis during elective stent-assisted coiling, with novel use of prasugrel as an alternative platelet inhibitor in the neurovascular setting.