RT Journal Article
SR Electronic
T1 Novel use of prasugrel for intracranial stent thrombosis
JF Journal of NeuroInterventional Surgery
JO J NeuroIntervent Surg
FD BMJ Publishing Group Ltd.
SP 358
OP 360
DO 10.1136/jnis.2010.004382
VO 3
IS 4
A1 Thabele M Leslie-Mazwi
A1 Ronil V Chandra
A1 Daniel C Oh
A1 Raul G Nogueira
YR 2011
UL http://jnis.bmj.com/content/3/4/358.abstract
AB Dual antiplatelet therapy is established for prevention of stent thrombosis in cardiac patients, and widely utilized in neurointerventional stent cases. Aspirin and clopidogrel are typically synergistic. We present a case of clopidogrel resistance due to genetic polymorphism resulting in acute stent thrombosis during elective stent-assisted coiling, with novel use of prasugrel as an alternative platelet inhibitor in the neurovascular setting.