PT - JOURNAL ARTICLE AU - Patel, Saharsh AU - Fargen, Kyle M AU - Peters, Keith AU - Krall, Peter AU - Samy, Hazem AU - Hoh, Brian L TI - Return of visual function after bilateral visual loss following flow diversion embolization of a giant ophthalmic aneurysm due to both reduction in mass effect and reduction in aneurysm pulsation AID - 10.1136/neurintsurg-2013-010960.rep DP - 2015 Jan 01 TA - Journal of NeuroInterventional Surgery PG - e1--e1 VI - 7 IP - 1 4099 - http://jnis.bmj.com/content/7/1/e1.short 4100 - http://jnis.bmj.com/content/7/1/e1.full SO - J NeuroIntervent Surg2015 Jan 01; 7 AB - Large and giant paraclinoid aneurysms are challenging to treat by either surgical or endovascular means. Visual dysfunction secondary to optic nerve compression and its relationship with aneurysm size, pulsation and thrombosis is poorly understood. We present a patient with a giant paraclinoid aneurysm resulting in bilateral visual loss that worsened following placement of a Pipeline Embolization Device and adjunctive coiling. Visual worsening occurred in conjunction with aneurysm thrombosis, increase in maximal aneurysm diameter and new adjacent edema. Her visual function spontaneously improved in a delayed fashion to better than pre-procedure, in conjunction with reduced aneurysmal mass effect, size and pulsation artifact on MRI. This report documents detailed ophthalmologic and MRI evidence for the role of thrombosis, aneurysm mass effect and aneurysm pulsation as causative etiologies for both cranial nerve dysfunction and delayed resolution following flow diversion treatment of large cerebral aneurysms.