PT  - JOURNAL ARTICLE
AU  - Hahnemann, M L
AU  - Ringelstein, A
AU  - Sandalcioglu, I E
AU  - Goericke, S
AU  - Moenninghoff, C
AU  - Wanke, I
AU  - Forsting, M
AU  - Sure, U
AU  - Schlamann, M
TI  - Silent embolism after stent-assisted coiling of cerebral aneurysms: diffusion-weighted MRI study of 75 cases
AID  - 10.1136/neurintsurg-2013-010820
DP  - 2014 Jul 01
TA  - Journal of NeuroInterventional Surgery
PG  - 461--465
VI  - 6
IP  - 6
4099  - http://jnis.bmj.com/content/6/6/461.short
4100  - http://jnis.bmj.com/content/6/6/461.full
SO  - J NeuroIntervent Surg2014 Jul 01; 6
AB  - Purpose New ischemic brain lesions are common findings after cerebral diagnostic angiography and endovascular therapy. Diffusion-weighted MRI (DWI) can be used for detection of these lesions. The aim of the present study was to investigate the incidence of DWI lesions after stent-assisted coiling and the evaluation of possible risk factors. Methods The study included a total of 75 consecutive patients treated with stent-assisted coiling. Post-procedural DWI of the brain was performed to detect ischemic lesions. Demographic data, aneurysm characteristics and angiographic parameters were correlated with properties of DWI lesions. Results In post-procedural DWI, 48 of the 75 patients (64%) had 163 DWI lesions in a pattern consistent with embolic events. The number of patients with DWI lesions was significantly increased in older patients (≥55 years) and longer intervention times (≥120 min). The ischemic brain volume was significantly increased in older patients (≥55 years) as well as in patients who were implanted with a shorter stent (<20 mm). Conclusions Thromboembolic events are common after stent-assisted coiling with an incidence comparable to DWI studies after coiling alone. Despite several devices and low operator experience, stent-assisted coiling for intracranial aneurysms has a very low risk of permanent neurologic disability. Further studies are necessary to improve the safety of stent-assisted coiling for patients in conditions with increased risk potential (age, procedure time, stent length).