PT  - JOURNAL ARTICLE
AU  - Pierre Bouillot
AU  - Olivier Brina
AU  - Rafik Ouared
AU  - Hasan Yilmaz
AU  - Karl-Olof Lovblad
AU  - Mohamed Farhat
AU  - Vitor Mendes Pereira
TI  - Computational fluid dynamics with stents: quantitative comparison with particle image velocimetry for three commercial off the shelf intracranial stents
AID  - 10.1136/neurintsurg-2014-011468
DP  - 2016 Mar 01
TA  - Journal of NeuroInterventional Surgery
PG  - 309--315
VI  - 8
IP  - 3
4099  - http://jnis.bmj.com/content/8/3/309.short
4100  - http://jnis.bmj.com/content/8/3/309.full
SO  - J NeuroIntervent Surg2016 Mar 01; 8
AB  - Background and purpose Validation of computational fluid dynamics (CFD) in stented intracranial aneurysms (IAs) is still lacking, to reliably predict prone to occlusion hemodynamics, probing, in particular, velocity reduction, and flow pattern changes. This study compares CFD outcome with particle imaging velocimetry (PIV) for three commercial off the shelf (COTS) stents of different material densities.Material and methods The recently developed uniform and high precision multi-time lag PIV method was applied to a sidewall aneurysm before and after implantation of three COTS stents with high, intermediate, and low material densities. The measured laser sheet flow patterns and velocity reductions were compared with CFD results and correlated with stent material density.Results Velocity reduction was in good agreement for unstented high and low porosity stented IA, while flow pattern change was fully matched for unstented and high porosity stented IA. Poor CFD–PIV matching in IA was found for intermediate porosity stents.Conclusions CFD reproduced fully PIV measurements in unstented and high porosity stented IAs. With low porosity stents, CFD reproduced velocity reduction and high velocities close to the neck, while a marked mismatch on sluggish flow was found at the dome. CFD was unable to match PIV with intermediate porosity stents for which hemodynamic transition occurred.