PT - JOURNAL ARTICLE AU - Travis R Ladner AU - Lucy He AU - Lori C Jordan AU - Calvin Cooper AU - Michael T Froehler AU - J Mocco TI - Mechanical thrombectomy for acute stroke in childhood: how much does restricted diffusion matter? AID - 10.1136/neurintsurg-2014-011465.rep DP - 2015 Dec 01 TA - Journal of NeuroInterventional Surgery PG - e40--e40 VI - 7 IP - 12 4099 - http://jnis.bmj.com/content/7/12/e40.short 4100 - http://jnis.bmj.com/content/7/12/e40.full SO - J NeuroIntervent Surg2015 Dec 01; 7 AB - Mechanical thrombectomy holds promise for children with large cerebral arterial occlusions, although there are few reports in this population. We report a case of retrievable stent-assisted mechanical thrombectomy in a 5-year-old with basilar artery occlusion, despite late presentation and extensive initial diffusion-weighted imaging (DWI) restriction. This resulted in successful Thrombolysis in Cerebral Infarction 2B reperfusion and excellent clinical outcome. At 6-week follow-up he was completely back to baseline with no residual deficits (pediatric stroke outcome measure=0, modified Rankin scale=0). At 3-month follow-up the patient has not had any recurrent stroke or concern for stroke-like symptoms. We review the literature on mechanical thrombectomy and DWI changes in acute stroke in early to middle childhood (<12 years old).