PT - JOURNAL ARTICLE AU - Christopher R Durst AU - David A Ornan AU - Michael A Reardon AU - Prachi Mehndiratta AU - Sugoto Mukherjee AU - Robert M Starke AU - Max Wintermark AU - Avery Evans AU - Mary E Jensen AU - R Webster Crowley AU - John Gaughen AU - Kenneth C Liu TI - Prevalence of dural venous sinus stenosis and hypoplasia in a generalized population AID - 10.1136/neurintsurg-2015-012147 DP - 2016 Nov 01 TA - Journal of NeuroInterventional Surgery PG - 1173--1177 VI - 8 IP - 11 4099 - http://jnis.bmj.com/content/8/11/1173.short 4100 - http://jnis.bmj.com/content/8/11/1173.full SO - J NeuroIntervent Surg2016 Nov 01; 8 AB - Background and purpose While recent literature has described the prevalence of transverse sinus stenosis in patients with idiopathic intracranial hypertension, tinnitus, and refractory headaches, it is unclear what the prevalence is in the general population. This study evaluates the prevalence of venous sinus stenosis and hypoplasia in the general patient population.Materials and methods 355 of 600 consecutive patients who underwent CT angiography of the head met the inclusion criteria. The diameters of the dural venous sinuses were recorded. Each study was evaluated by a neuroradiologist for the presence of stenoses. Univariate and multivariate statistical analyses were performed by a statistician.Results The prevalence of unilateral transverse sinus stenosis or hypoplasia in a sample of patients representing the general population was 33%, the prevalence of bilateral transverse sinus stenosis was 5%, and the prevalence of unilateral stenosis with contralateral hypoplasia was 1%. A multivariate analysis identified arachnoid granulations as a predictor of stenosis (p<0.001). Gender trended toward significance (p=0.094). Race was not a significant predictor of stenosis (p=0.745).Conclusions The prevalence of bilateral transverse sinus stenosis in the general population is not trivial. These data may be used as a reference for understanding the mechanistic role of stenoses in idiopathic intracranial hypertension, tinnitus, and refractory headaches.