RT Journal Article
SR Electronic
T1 Prevalence of dural venous sinus stenosis and hypoplasia in a generalized population
JF Journal of NeuroInterventional Surgery
JO J NeuroIntervent Surg
FD BMJ Publishing Group Ltd.
SP 1173
OP 1177
DO 10.1136/neurintsurg-2015-012147
VO 8
IS 11
A1 Christopher R Durst
A1 David A Ornan
A1 Michael A Reardon
A1 Prachi Mehndiratta
A1 Sugoto Mukherjee
A1 Robert M Starke
A1 Max Wintermark
A1 Avery Evans
A1 Mary E Jensen
A1 R Webster Crowley
A1 John Gaughen
A1 Kenneth C Liu
YR 2016
UL http://jnis.bmj.com/content/8/11/1173.abstract
AB Background and purpose While recent literature has described the prevalence of transverse sinus stenosis in patients with idiopathic intracranial hypertension, tinnitus, and refractory headaches, it is unclear what the prevalence is in the general population. This study evaluates the prevalence of venous sinus stenosis and hypoplasia in the general patient population.Materials and methods 355 of 600 consecutive patients who underwent CT angiography of the head met the inclusion criteria. The diameters of the dural venous sinuses were recorded. Each study was evaluated by a neuroradiologist for the presence of stenoses. Univariate and multivariate statistical analyses were performed by a statistician.Results The prevalence of unilateral transverse sinus stenosis or hypoplasia in a sample of patients representing the general population was 33%, the prevalence of bilateral transverse sinus stenosis was 5%, and the prevalence of unilateral stenosis with contralateral hypoplasia was 1%. A multivariate analysis identified arachnoid granulations as a predictor of stenosis (p<0.001). Gender trended toward significance (p=0.094). Race was not a significant predictor of stenosis (p=0.745).Conclusions The prevalence of bilateral transverse sinus stenosis in the general population is not trivial. These data may be used as a reference for understanding the mechanistic role of stenoses in idiopathic intracranial hypertension, tinnitus, and refractory headaches.