RT Journal Article
SR Electronic
T1 Mid-term and long-term follow-up of intracranial aneurysms treated by the p64 Flow Modulation Device: a multicenter experience
JF Journal of NeuroInterventional Surgery
JO J NeuroIntervent Surg
FD BMJ Publishing Group Ltd.
SP 70
OP 76
DO 10.1136/neurintsurg-2016-012502
VO 9
IS 1
A1 Francesco Briganti
A1 Giuseppe Leone
A1 Lorenzo Ugga
A1 Mariano Marseglia
A1 Antonio Macera
A1 Andrea Manto
A1 Luigi Delehaye
A1 Maurizio Resta
A1 Mariachiara Resta
A1 Nicola Burdi
A1 Nunzio Paolo Nuzzi
A1 Ignazio Divenuto
A1 Ferdinando Caranci
A1 Mario Muto
A1 Domenico Solari
A1 Paolo Cappabianca
A1 Francesco Maiuri
YR 2017
UL http://jnis.bmj.com/content/9/1/70.abstract
AB Background Experience with the endovascular treatment of cerebral aneurysms using the p64 Flow Modulation Device is still limited. This study discusses the results and complications of this new flow diverter device.Methods 40 patients (30 women, 10 men) with 50 cerebral aneurysms treated in six Italian neurointerventional centers with the p64 Flow Modulation Device between April 2013 and September 2015 were retrospectively reviewed.Results Complete occlusion was obtained in 44/50 aneurysms (88%) and partial occlusion in 3 (6%). In the other three aneurysms (6%), two cases of asymptomatic in-stent thrombosis and one intraprocedural occlusion of the parent vessel occurred. Technical complications were observed in eight procedures (16%). Permanent morbidity due to acute in-stent thrombosis and consequent ischemic stroke occurred in one patient (2.5%). No delayed aneurysm rupture, subarachnoid or intraparenchymal hemorrhage, or ischemic complications occurred and there were no deaths.Conclusions Endovascular treatment with the p64 Flow Modulation Device is a safe treatment for unruptured cerebral aneurysms, resulting in a high rate of occlusion. As with other flow diverter devices, we recommend this treatment mainly for large-necked aneurysms of the internal carotid artery siphon. However, endovascular treatment with the p64 device should also be encouraged in difficult cases such as aneurysms of the posterior circulation and beyond the circle of Willis.