TY - JOUR T1 - Vein of Galen aneurysmal malformation—clinical and angiographic spectrum with management perspective: an institutional experience JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 159 LP - 164 DO - 10.1136/neurintsurg-2015-012137 VL - 9 IS - 2 AU - Himanshu Agarwal AU - Leve Joseph Devarajan Sebastian AU - Shailesh B Gaikwad AU - Ajay Garg AU - Nalini K Mishra Y1 - 2017/02/01 UR - http://jnis.bmj.com/content/9/2/159.abstract N2 - Background and purpose Vein of Galen aneurysmal malformation (VGAM) is a rare developmental intracranial vascular malformation. We analyzed the clinical presentations, imaging findings, angioarchitecture, management options, and outcome in a demographically heterogeneous set of VGAM patients.Methods We retrospectively analyzed cases of VGAM from our departmental archive collected between 1988 and January 2015. Demographic, clinical, therapeutic, and follow-up details were obtained for each patient from the available records.Results We identified 36 patients with VGAM including 6 neonates, 18 infants, 7 children aged 2–10 years, and 5 adults. Macrocrania was the commonest presenting feature. Type of fistulae was mural in 14 and choroidal in 18 patients while 4 had a thrombosed sac at presentation. In 3 cases the dilated venous sac had connection with the deep venous system. Bilateral jugular atresia and stenosis were seen in 9 and 6 patients, respectively. Giant venous sac (>4 cm) was significantly correlated with mural type (p=0.0001). Dural arterial recruitment was seen in 4 patients including 3 adults. Among the 23 patients treated by endovascular means, 14 had a good outcome, 5 had a poor outcome, and 4 died. A significant correlation was noted between jugular atresia and poor outcome (p=0.003).Conclusions We encountered a wide range of demographic, clinical, and angiographic features in VGAM. Mural type malformations were associated with giant venous sacs. Good outcome after embolization was seen in selected neonates and in most of the infants, children, and adults. Jugular atresia was significantly associated with poor outcome. ER -