@article {Dabus419, author = {Guilherme Dabus and Lotfi Hacein-Bey and Bahram Varjavand and R Dana Tomalty and Patrick P Han and Vadim Yerokhin and Italo Linfante and J Mocco and Thomas Oxley and Alejandro Spiotta and M Imran Chaudry and Raymond D Turner and Aquilla S Turk}, title = {Safety, immediate and mid-term results of the newer generation of hydrogel coils in the treatment of ruptured aneurysms: a multicenter study}, volume = {9}, number = {4}, pages = {419--424}, year = {2017}, doi = {10.1136/neurintsurg-2016-012780}, publisher = {British Medical Journal Publishing Group}, abstract = {Objective To assess the {\textquoteleft}real-world{\textquoteright} performance of the newer generation of hydrogel coils in ruptured aneurysms.Methods A multicenter retrospective study was carried out of angiographic and clinical outcome data on consecutive patients with ruptured aneurysms treated with at least 70\% of the newer generation of hydrogel coils. Demographics and data on clinical grade, smoking, use of statins, aneurysm size, location, technique used, packing density, immediate angiographic result, angiographic follow-up, rebleeding and clinical outcome were obtained and analyzed.Results Eighty patients (54F; 26M) with an average age of 55.1 years were entered in the study. Forty-four presented good clinical grade (Hunt and Hess 1 or 2). Forty-two (52.5\%) aneurysms were <=5 mm. 56.7\% of the aneurysms were treated with simple coil embolization and 39.6\% with balloon-assisted coil. The packing density ranged from 9.3\% to 92.6\% (mean 48.5\%). Immediate occlusion rates (Raymond{\textendash}Roy Scale) were: complete occlusion (class I) in 57.5\%, residual neck (class II) in 32.5\% and residual aneurysm (class III) in 10\%. Intraoperative rupture occurred in 3 cases (3.75\%). Clinical follow-up, available in 73 patients, showed a good outcome (modified Rankin Scale 0{\textendash}2) in 76.3\%. Preliminary data on imaging follow-up were available in 54 patients (average 6.8 months) with complete occlusion in 77.8\%, residual neck in 20.3\% and residual aneurysm in 1.9\%. There was no re-hemorrhage.Conclusions Our data show that the use of the newer-generation hydrogel coils in the treatment of ruptured aneurysms is feasible, safe and effective with high immediate and mid-term occlusion rates and low morbidity.}, issn = {1759-8478}, URL = {https://jnis.bmj.com/content/9/4/419}, eprint = {https://jnis.bmj.com/content/9/4/419.full.pdf}, journal = {Journal of NeuroInterventional Surgery} }