TY - JOUR T1 - Flat-detector computed tomography PBV map in the evaluation of presurgical embolization for hypervascular brain tumors JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 1139 LP - 1144 DO - 10.1136/neurintsurg-2016-012658 VL - 9 IS - 11 AU - Li-Li Wen AU - Xin Zhang AU - Qing-Rong Zhang AU - Qi Wu AU - Shu-Juan Chen AU - Jin-Long Deng AU - Kaiyi Huang AU - Han-Dong Wang Y1 - 2017/11/01 UR - http://jnis.bmj.com/content/9/11/1139.abstract N2 - Background Preoperative embolization of hypervascular brain tumors is frequently used to minimize intraoperative bleeding.Objective To explore the efficacy of embolization using flat-detector CT (FDCT) parenchymal blood volume (PBV) maps before and after the intervention.Materials and methods Twenty-five patients with hypervascular brain tumors prospectively received pre- and postprocedural FDCT PBV scans using a biplane system under a protocol approved by the institutional research ethics committee. Semiquantitative analysis, based on region of interest measurements of the pre- and post-embolization PBV maps, operating time, and blood loss, was performed to assess the feasibility of PBV maps in detecting the perfusion deficit and to evaluate the efficacy of embolization.Results Preoperative embolization was successful in 18 patients. The relative PBV decreased significantly from 3.98±1.41 before embolization to 2.10±2.00 after embolization. Seventeen patients underwent surgical removal of tumors 24 hours after embolization. The post-embolic tumor perfusion index correlated significantly with blood loss (ρ=0.55) and operating time (ρ=0.60).Conclusions FDCT PBV mapping is a useful method for evaluating the perfusion of hypervascular brain tumors and the efficacy of embolization. It can be used as a supplement to CT perfusion, MRI, and DSA in the evaluation of tumor embolization. ER -